8/4/2023 0 Comments Total hygiene dm1 spray![]() Head and neck cancer (HNC) actually includes many different malignancies. 13 These factors may ultimately cause reduced nutritional intake and weight loss and significantly affect general health and quality of life of the subjects involved. Objectively, patients affected by xerostomia have a hypofunction of the salivary output 11, 12 leading to functional oral disorders such as sore throat, altered taste, dental decay, changes in voice quality, and impaired chewing and swallowing function. immunoglobulins, proteins, and enzymes provide antibacterial action.calcium, phosphates, and proteins work together as an antisolubility factor and modulate demineralization and remineralization of tooth surfaces.macromolecule proteins and mucins serve to cleanse, aggregate, and/or attach oral microorganisms and contribute to the dental plaque metabolism.bicarbonates, phosphates, and urea act to modulate pH and the buffering capacity of saliva.10 Saliva components interact in related functions in the following general areas: Major salivary glands contribute to most of the secretion volume and electrolyte content of saliva (the parotid, submandibular, and sublingual glands, which account for 90% of saliva production), whereas minor salivary glands contribute little secretion volume and most of the blood-group substance. Saliva is an important host defense component of the oral cavity. A large variety of causes can lead to xerostomia, eg, radiotherapy and chemotherapy, 1– 4 the chronic use of drugs, 5– 7 and rheumatic and dysmetabolic diseases. ![]() Xerostomia is a term used to describe the subjective symptoms of a dry mouth deriving from a lack of saliva. Keywords: radiation-induced xerostomia, salivary gland hypofunction, management strategies A preventive approach and the correct treatment of the particular radiotherapeutic patient can help to improve the condition of xerostomia. It could depend on the type of cancer treatment and the cumulative radiation dose to the gland tissue. In addition, a modified diet and the patient’s motivation to enhance oral hygiene can lead to a significant improvement.Ĭonclusion: Radiation-induced xerostomia could be considered a multifactorial disease. The systematic review of the literature suggests that the most suitable methods for managing the clinical and pathophysiological consequences of HNC radiotherapy might be the pharmacological approach, for example, through the use of cholinergic agonists when residual secretory capacity is still present, and the use of salivary substitutes. Results: Sixty-one articles met the inclusion criteria. Two reviewers independently screened and included papers according to the predefined selection criteria. Methods: MEDLINE/PubMed and the Cochrane Library databases were electronically evaluated for articles published from January 1, 1970, to June 30, 2013. Purpose: To analyze the literature of actual management strategies for radiation-induced hypofunction and xerostomia in HNC patients. The resulting salivary gland hypofunction and xerostomia seriously reduce the patient’s quality of life. Roberto Pinna, 1 Guglielmo Campus, 2 Enzo Cumbo, 3 Ida Mura, 1 Egle Milia 2ġDepartment of Biomedical Science, 2Department of Surgery, Microsurgery and Medicine, University of Sassari, Sassari, 3Department of Dental Science, University of Palermo, Palermo, Italyīackground: The irradiation of head and neck cancer (HNC) often causes damage to the salivary glands.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |